R-422C (One Shot)* is a low temperature retrofit blend from ICOR with properties very similar to R-404A. It can directly replace R-502, R-402A/B, R-408A, R-404A and R-507. R-22 low-temp systems can also be retrofitted to R-422C with some component changes (TXVs, for example). With increased regulatory pressure on leakage and recordkeeping of ozone-depleting refrigerants, R-422C offers an HFC-based retrofit solution for R-502 and the HCFC-based low temperature blends. *One Shot is a registered trademark of ICOR.

The hydrocarbon component in R-422C helps promote oil return in systems containing mineral oil or alkylbenzene. Although HFC refrigerants won’t mix with these oils, the hydrocarbon addition thins the oil and keeps it moving around the loop. More complicated piping arrangements or large hold-up volumes may still require some oil be changed to POE.

Part NumberDescription


Download SDS for R-422C.

Download the R-422C product information
from the NRI Refrigerant Reference Guide